This company was started in July 2002 for the purpose of bringing these
new methods of preparation of tissues for frozen sections to my colleagues
in pathology. I have been practicing surgical pathology at Hackensack
University Medical Center in New Jersey for 22 years. The pathologists cut
the frozen sections at our hospital. Over the years I have been confronted
numerous times with impossible embedding tasks. I have been swamped with
specimens on a daily basis, forced to wait and watch as I applied the heat
extractor weight to each block. Over the past 10 years I have been working
on methods to overcome these difficult situations. Much of this has been
accomplished with tools in my basement. The result of these efforts are
this simple set of apparatus which we have used in our hospital with great
success for the last 7 years.
All of the manufacturing of this apparatus is done locally in the USA and
I have to thank these terrific manufactures who have helped me get started
by trying to keep the costs down in such small numbers. All of the
freezing apparatus and chucks are made of stainless steel and are pretty
much indestructible. Stainless steel is very hard and expensive to
machine. I have priced these items as low as possible. It would have been
much less expensive to make the chucks from aluminum but it does not have
the same freezing capacity. Aluminum is warmed by the
embedding medium rather than to freeze it.
Would we ever consider paraffin embedding tissue by putting the tissue on
a chuck, dripping wax on it and squashing it with a weight? My goal is to
get users to realize this is the way it should have been done 100 years
ago, and maybe the cryostat manufacturers will follow suit. Then I can go
back to a normal lifestyle.
This company consists of me, my wife and a couple of pets barking in the
background. Right now my facility consists of a lot of large shelves in
what was my
study, a desk in the family room where Jeannine works and the workshop in my basement where I have been doing some of the
final finishing duties. So if you are wondering why you may get an
answering machine if you call, my wife may be picking up the kids.
I have made this all sound pretty high
tech....don't ya think?
Some of the best things are home grown.
I am pretty sure most people who give it a serious trial will not look
forward to going back to conventional methods. And if the world of
pathology still wants to accept frozen section as a inferior technique
fraught with limitations......at least I still have my day job!
 |
|
Stephen Peters M.D. |
2005 Update:
Well we are still here! I am happy to say the Precision Cryoembedding
System is being used in almost 400 hospitals now. Many of them are major academic institutions
research facilities and biotech companies. We are getting a lot of
additional orders and referrals to other hospitals. I take this as a sign
that my customers are appreciating the advantages of preparing frozen
sections using these simple techniques.
I am very exited to say that others companies have expressed interest in
promoting the Precision Cryoembedding System.
Leica Microsystems is offering the
system as an accessory in their cryostats and others, and is making the system available
throughout the world. I have always been a big fan of their
cryostats and microscopes. For me this is an honor. I give them a lot of
credit, they are able to recognize new ideas worth exploring.
Pacific Southwest Lab Equipment Inc. is
also offering the system to their US customers.
I really appreciate these companies helping
me to bring these techniques to our colleagues. I know it is a change from
our present methods. But I am confident anyone who is willing to try
something new will be rewarded with dramatic improvements in their ability
to provide these important results to patients and surgeons. And for my
colleagues who have passed these techniques to others, I am indebted.

2006 Update
The Precision Cryoembedding System is now being used in over 500
institutions and growing. I continue to received very positive feedback
from users of our system. I am confident that our efforts are being
appreciated. I am happy to say Dae Myung Science Company is now offering
our products to their customers in S. Korea.
We will be adding a small increase to our prices in 2007 to
keep up with costs. My wife Jeannine and I continue to run this business
from our home with little overhead allowing us to keep our prices at
a minimum. Our profits have been modest, but we remain in the green on a
mission to bring these new and better methods to the fields of
pathology, histology and scientific research.
I truly appreciate the help of our customers and
distributors in helping to spread these new methods to our
colleagues.

2009 Update
Our system has found it's way into about 1000 institutions,
including hospitals, dermatologic surgery practices and many research
institutions. We have customers on 6 continents. We continue to receive
numerous wonderful letters from users who are appreciating the advantages
of the Precision Cryoembedding System and are grateul to them for taking
the time to try something new. We continue to work closely with
Leica Microsystems and also distribute through Fisher Scientific, and a
number of regional histology equipment suppliers. Leica has incorporated
our system into the excellent new CM 1950 cryostat which I am proud to say
I was asked to provide input in the design process. I have also
recently submitted a book to Springer Verlag titled "a Practical
Guide to Frozen Section Technique" which I am hoping to see in print
around the end of the year. The book contains everything I have learned
about frozen section technique from grossing to reading the slides over 26
years of surgical pathology practice. It also contains chapters on Mohs
technique by the great teacher of Mohs technique, Barbara Beck, animal
research techniques by noted expert Dr Charles Scouten and a
chapter on understanding the cryostat by Philip Hyam who spent his career
in the cryostat industry with Leica in Canada.
My wife Jeannine who has always cared for the bookwork side
of our little mission has begun joining me on exhibits now that the kids
are off to college. She is an enormous help and can breaks down our booth
like she is doing the dishes. I have to keep out of her way. We are
receiving more and more new customers as referrals and as users change
positions. We have also had several articles written independently by
users wanting to share our advances with colleagues and are very grateful
for all of our family of users who have helped us to spread the word of
the value of these new techniques.
2011 Update
Still
here and growing. There are now somewhere in the range of 1500
institutions using the Precision Cryoembedding System at this point. We
continue to partner with Leica Biosystems who has been a strong supporter
of our technology since our start. We are grateful to them and am happy to
be sharing with their customers around the world. We are also grateful to
Fischer Scientific, Pacific Southwest Instrument Company, and Belair
Scientific who continue to help us share our techniques.
We are delighted to add Electron Microscopy Sciences and Immunohistochemistry.com
to our family who are also now sharing in our mission.
I am proud
to say our apparatus continues to be manufactured locally, by Dualtron
Manufacturing of West Babylon, NY. From the beginning their president saw
the importance in what we were doing and made us whatever we needed in
quantities we could afford.
It is
now becoming more obvious that our methods are spreading on their own. As
new residents trained in our methods emerge, they are bringing these
techniques to there new practices. As our users change positions, they
bring it to their new sites. I believe the seeds we have planted are
growing nicely. Thank you to all our customers who help us share these
techniques with colleagues.
I
am happy to say I have transitioned from the community to academia in 2009
when I took the position of Director of Surgical Pathology at University
Hospital, Newark and University of Medicine and Dentistry of New Jersey. I
have found the teaching environment very stimulating. Surrounded by hungry
young minds and awesome cases at another level of difficulty,
I am learning as much as I am teaching. It is wonderful to be able
to share what one has learned.
And speaking of sharing, my true partner and wonderful wife of 36 years,
Jeannine continues to increasingly share the duties at PI. I could not do
this without her. And if you are wondering how we can sell chucks made
from stainless steal for the same price as our our competitors sell chucks
made from aluminum,
it is because we do it all our selves.
